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SERA:NASDAQSera Prognostics, Inc. Analysis

Data as of 2026-04-30 - not real-time

$1.99

Latest Price

8/10Risk

Risk Level: High

Executive Summary

Sera Prognostics is trading at $1.99, barely above its computed support of $1.91 and well below the 20‑day SMA of $2.13, indicating limited upside in the near term. The RSI sits at 43, suggesting neutral momentum, while the MACD histogram is negative and the MACD signal is labeled bearish, reinforcing a short‑term downtrend. Volatility is extreme at 83% over the past 30 days and the beta of 1.75 signals the stock moves more aggressively than the market, amplifying price swings. Fundamental metrics are distressing: revenue has collapsed by 58%, gross margin is deeply negative, and operating cash flow is a $25.6 M outflow, highlighting severe profitability challenges. Despite a healthy cash balance of $39 M, the company is burning cash faster than it can generate, and the debt‑to‑equity ratio of 3.1, though numerically modest against cash, underscores leverage concerns. The price‑to‑sales multiple of 962× and a negative PE further suggest the market is pricing in speculative expectations rather than solid earnings.
From a valuation standpoint, the price‑to‑book ratio of roughly 1.0 hints at a fair valuation relative to assets, but the inflated sales multiple and negative earnings point to an overvalued equity on a earnings basis. The healthcare/medical‑devices sector carries inherent regulatory risk, which is heightened for a company reliant on diagnostic approvals. Liquidity is tightening, with decreasing volume and average daily volumes well below the market cap, raising concerns about trade execution. Overall, the blend of weak fundamentals, high volatility, and bearish technical signals makes SERA a high‑risk holding with limited short‑term upside.

Market Outlook

Short Term

< 1 year
Cautious
Model confidence: 7/10

Key Factors

  • Bearish MACD and negative histogram
  • Price hovering just above support with limited upside
  • High volatility and decreasing volume

Medium Term

1–3 years
Neutral
Model confidence: 5/10

Key Factors

  • Continued cash burn and negative margins
  • Uncertain regulatory path for diagnostic tests
  • Potential runway from existing cash reserves

Long Term

> 3 years
Neutral
Model confidence: 4/10

Key Factors

  • Long‑term growth potential of blood‑based biomarker platform
  • Risk of further dilution if additional financing is needed
  • Dependence on successful product commercialization and reimbursement

Key Metrics & Analysis

Financial Health

Revenue Growth-58.30%
P/E Ratio-2.9
ROE-51.83%
ROA-26.15%
Debt/Equity3.10
P/B Ratio1.0
Op. Cash Flow$-25623000
Free Cash Flow$-17447624
Industry P/E25.2

Technical Analysis

TrendNeutral
RSI43.3
Support$1.91
Resistance$2.36
MA 20$2.13
MA 50$2.10
MA 200$2.82
MACDBearish
VolumeDecreasing
Fear & Greed Index88.36

Valuation

Target Price$5.00
Upside/Downside151.26%
GradeOvervalued
TypeValue

Risk Assessment

Beta1.75
Volatility83.18%
Sector RiskMedium
Reg. RiskHigh
Geo RiskLow
Currency RiskLow
Liquidity RiskHigh

This analysis may contain inaccuracies and is provided for informational and research purposes only. It is not personal investment advice, a recommendation, or an instruction to buy, sell, or hold any asset.