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NBIX:NASDAQNeurocrine Biosciences, Inc. Analysis

Data as of 2026-05-20 - not real-time

$154.36

Latest Price

6/10Risk

Risk Level: Medium

Executive Summary

Neurocrine Biosciences is trading at $154.36, comfortably above its 20‑day SMA of $142.73 and its 50‑day SMA of $135.21, indicating short‑term strength. The MACD line sits at 7.22 well above the signal line (5.76) and a bullish histogram, while the RSI of 66.5 suggests the stock is approaching overbought territory but still has momentum. Volatility remains high at 37.4% over the past 30 days, yet the beta of 0.83 points to a modest correlation with the broader market, tempering systematic risk. Fundamentals are compelling: revenue surged 42% YoY to $3.10 B, gross margin is a healthy 64%, and free cash flow exceeds $590 M, supporting the strong_buy consensus from 27 analysts. The DCF‑derived fair value of $216.10 implies roughly a 24% upside, and the forward PE of 12.1 is well below the industry average of 27.2, underscoring an undervalued position. Recent material news highlights a record Q1 product sales run‑rate of $811 M, the launch of VYKAT XR for Prader‑Willi syndrome, and the completion of the Soleno Therapeutics acquisition, expanding the rare‑disease pipeline. The company's pipeline breadth—from movement disorders to metabolic diseases—adds long‑term growth catalysts. While the fear‑greed index signals “Extreme Greed,” the stock’s solid balance sheet (cash > $1.3 B, debt‑to‑equity ~13.6) and low dividend policy keep capital allocation flexible. Overall, the blend of strong earnings momentum, attractive valuation gaps, and strategic pipeline expansion positions NBIX for continued upside.
Investors should watch for any regulatory setbacks in the newly approved VYKAT XR and integration progress of Soleno, but the current technical and fundamental backdrop supports a bullish outlook across horizons.

Market Outlook

Short Term

< 1 year
Neutral
Model confidence: 7/10

Key Factors

  • Bullish MACD and price above short‑term SMAs
  • RSI near overbought levels suggests caution
  • Increasing volume supports current momentum

Medium Term

1–3 years
Positive
Model confidence: 8/10

Key Factors

  • Revenue growth of 42% and expanding rare‑disease portfolio
  • DCF fair value indicating ~24% upside
  • Forward PE of 12.1 versus industry average of 27.2

Long Term

> 3 years
Positive
Model confidence: 9/10

Key Factors

  • Robust pipeline with multiple late‑stage candidates
  • Strong free cash flow generation and low leverage
  • Strategic acquisition of Soleno Therapeutics enhancing endocrinology franchise

Key Metrics & Analysis

Financial Health

Revenue Growth42.20%
Profit Margin21.55%
P/E Ratio23.7
ROE22.50%
ROA11.62%
Debt/Equity13.60
P/B Ratio4.6
Op. Cash Flow$863.7M
Free Cash Flow$590.6M
Industry P/E27.2

Technical Analysis

TrendNeutral
RSI66.5
Support$126.49
Resistance$162.39
MA 20$142.73
MA 50$135.21
MA 200$138.45
MACDBullish
VolumeIncreasing
Fear & Greed Index89.09

Valuation

Fair Value$216.11
Target Price$190.99
Upside/Downside23.73%
GradeUndervalued
TypeGrowth

Risk Assessment

Beta0.83
Volatility37.44%
Sector RiskMedium
Reg. RiskHigh
Geo RiskLow
Currency RiskLow
Liquidity RiskLow

This analysis may contain inaccuracies and is provided for informational and research purposes only. It is not personal investment advice, a recommendation, or an instruction to buy, sell, or hold any asset.