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TNYA:NASDAQTenaya Therapeutics, Inc. Analysis

Data as of 2026-05-27 - not real-time

$0.79

Latest Price

8/10Risk

Risk Level: High

Executive Summary

Tenaya Therapeutics is trading at $0.79, below its 20‑day SMA of $0.83 and its 200‑day SMA of $1.03, while the 50‑day SMA sits at $0.76, indicating a short‑term price weakness but a longer‑term downtrend. The RSI of 48.7 suggests the stock is neither overbought nor oversold, and the MACD histogram is negative, confirming a bearish momentum signal. However, the stock’s 30‑day volatility is extreme at 91.8% and its beta of ~2.9 makes it highly responsive to market swings, amplifying both upside and downside risk.
On the fundamentals side, Tenaya holds $80.9 M in cash against a modest $10.1 M debt load, but it is burning cash at roughly $64 M annually and reports no meaningful revenue, resulting in deep operating losses. Despite a negative PE and a price‑to‑sales multiple of 764×, analysts rate the stock a “strong_buy” with a mean target of $4.00, implying a potential upside of over 400%. Recent earnings showed a modest surprise (+4.3%) and the company is set to present Phase 1b/2 data for its TN‑401 gene therapy at ASGCT 2026, which could serve as a catalyst for price appreciation.

Market Outlook

Short Term

< 1 year
Positive
Model confidence: 6/10

Key Factors

  • Quarterly earnings beat (+4.3%) provides near‑term positive sentiment
  • Upcoming ASGCT presentation of TN‑401 data could trigger a catalyst
  • Technical downside bias (price below SMA20, bearish MACD) suggests buying on dip

Medium Term

1–3 years
Positive
Model confidence: 8/10

Key Factors

  • Strong cash runway ($80.9 M) relative to cash burn
  • Analyst consensus strong‑buy with median target $3.5, indicating >300% upside
  • Progressing pipeline of gene‑therapy candidates for cardiomyopathy

Long Term

> 3 years
Positive
Model confidence: 9/10

Key Factors

  • Potential market‑changing gene‑therapy platform for heart disease
  • Strategic collaboration with Alnylam expanding target validation capabilities
  • High long‑term upside potential (≈405% upside/downside metric) despite current losses

Key Metrics & Analysis

Financial Health

P/E Ratio-1.9
ROE-73.59%
ROA-38.46%
Debt/Equity9.53
P/B Ratio1.4
Op. Cash Flow$-64386000
Free Cash Flow$-41898248
Industry P/E27.4

Technical Analysis

TrendNeutral
RSI48.7
Support$0.65
Resistance$1.15
MA 20$0.83
MA 50$0.76
MA 200$1.03
MACDBearish
VolumeDecreasing
Fear & Greed Index92.34

Valuation

Target Price$4.00
Upside/Downside404.99%
GradeUndervalued
TypeGrowth

Risk Assessment

Beta2.94
Volatility91.81%
Sector RiskHigh
Reg. RiskHigh
Geo RiskLow
Currency RiskLow
Liquidity RiskMedium

This analysis may contain inaccuracies and is provided for informational and research purposes only. It is not personal investment advice, a recommendation, or an instruction to buy, sell, or hold any asset.