SPRO:NASDAQSpero Therapeutics, Inc. Analysis
Data as of 2026-09-01 - not real-time
$1.22
Latest Price
9/10Risk
Risk Level: High
Executive Summary
The moving-average structure behind Spero Therapeutics, Inc. is bearish at $1.22, with short-term averages lagging the long-term ones. Across the trailing 30 sessions it lost 15.3%. RSI sits at 37.7, which reads as approaching oversold, and MACD momentum is bullish. Price has been bracketed by support at $1.15 and resistance at $1.30.
Valuation screens as undervalued: a P/E of 8.7 sits below the sector average of 30.4. Consensus targets land 227.9% above where the shares trade now.
Risk comes out at 9 of a possible 10, a high reading. With 30-day volatility of 50.5%, a beta of 1.47 and a maximum drawdown of 61.4%, position sizing matters more than entry timing here. The wider market backdrop reads extreme greed at 93 on the fear-greed composite.
The horizons diverge: hold near-term but buy on a long view, at 5/10 conviction over the longer horizon.
Valuation screens as undervalued: a P/E of 8.7 sits below the sector average of 30.4. Consensus targets land 227.9% above where the shares trade now.
Risk comes out at 9 of a possible 10, a high reading. With 30-day volatility of 50.5%, a beta of 1.47 and a maximum drawdown of 61.4%, position sizing matters more than entry timing here. The wider market backdrop reads extreme greed at 93 on the fear-greed composite.
The horizons diverge: hold near-term but buy on a long view, at 5/10 conviction over the longer horizon.
Top Market Events
SPRO strengthens its balance sheet and extends cash runway into 2029 while advancing its new SP001 immunology pipeline...Yahoo Finance19dSpero Therapeutics Inc SPRO Q2 2026 Earnings Call Highlights: FDA Approval of Utebzi and .CAMBRIDGE, Mass., Aug. 04, 2026 GLOBE NEWSWIRE -- Spero Therapeutics, Inc. Nasdaq: SPRO , a clinical-stage...
Market Outlook
Short Term
< 1 yearNeutral
Model confidence: 1/10
Key Factors
- Short-term moving averages stacked below long-term ones
- Trading below the 200-day average of 2.24
- MACD momentum is positive
Medium Term
1–3 yearsNeutral
Model confidence: 3/10
Key Factors
- Short-term moving averages stacked below long-term ones
- P/E of 8.7 versus sector average of 30.4
- Trading below the 200-day average of 2.24
Long Term
> 3 yearsPositive
Model confidence: 5/10
Key Factors
- P/E of 8.7 versus sector average of 30.4
- Analyst targets imply +227.9% versus the current price
- Profit margin of 15.7% is healthy
Key Metrics & Analysis
Financial Health
Profit Margin15.71%
P/E Ratio8.7
ROE19.17%
ROA7.19%
Debt/Equity4.62
P/B Ratio1.6
Op. Cash Flow$19.6M
Free Cash Flow$28.8M
Industry P/E30.4
Technical Analysis
TrendBearish
RSI37.7
Support$1.15
Resistance$1.30
MA 20$1.22
MA 50$1.54
MA 200$2.24
MACDBullish
VolumeDecreasing
Fear & Greed Index93.09
Valuation
Fair Value$7.14
Target Price$4.00
Upside/Downside227.87%
GradeUndervalued
TypeBlend
Risk Assessment
Beta1.47
Volatility50.48%
Sector RiskMedium
Reg. RiskHigh
Geo RiskLow
Currency RiskLow
Liquidity RiskMedium
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This analysis may contain inaccuracies and is provided for informational and research purposes only. It is not personal investment advice, a recommendation, or an instruction to buy, sell, or hold any asset.