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PSNL:NASDAQPersonalis, Inc. analysis

Data as of Sep 26, 2026 - not real-time

Latest price
$16.46
Risk: high
9/10High risk

Summary

Personalis, Inc. trades at $16.46, with its short-term moving averages stacked above the longer-term ones — a bullish trend structure. Across the trailing 30 sessions it gained 14.1%. Relative strength is 55.6 — neutral — and the MACD signal is bearish. Watch $15.91 as support and $17.38 as the nearer resistance level.
The company is not currently profitable on a trailing basis, so earnings multiples offer no valuation support. Consensus targets land 6.2% below where the shares trade now. Revenue is growing at 30.0% on a -153.8% profit margin.
Risk comes out at 9 of a possible 10, a high reading. With 30-day volatility of 57.6%, a beta of 2.78 and a maximum drawdown of 55.2%, position sizing matters more than entry timing here. The wider market backdrop reads extreme greed at 95 on the fear-greed composite.
Timeframes disagree: the short-term read is hold while the long-term read is sell, conviction 4 out of 10.

Market outlook

Short term

< 1 year

Neutral

Model confidence1/101 out of 10

Key factors

  • Short-term moving averages stacked above long-term ones
  • Trading above the 200-day average of 10.35
  • MACD momentum is negative

Medium term

1–3 years

Neutral

Model confidence2/102 out of 10

Key factors

  • Short-term moving averages stacked above long-term ones
  • Trading above the 200-day average of 10.35
  • Analyst targets imply -6.2% versus the current price

Long term

> 3 years

Cautious

Model confidence4/104 out of 10

Key factors

  • Negative profit margin of -153.8%
  • Analyst targets imply -6.2% versus the current price
  • Negative return on equity of -50.3%

Key metrics

Financial health

Revenue Growth30.00%
Profit Margin-153.84%
P/E Ratio-17.5
ROE-50.32%
ROA-25.03%
Debt/Equity16.16
P/B Ratio7.4
Op. Cash Flow$-92298000
Free Cash Flow$-56028248
Industry P/E30.5

Technical analysis

TrendBullish
RSI55.6
Support$15.91
Resistance$17.38
MA 20$16.52
MA 50$15.10
MA 200$10.35
MACDBearish
VolumeDecreasing
Fear & Greed Index94.88

Valuation

Target Price$15.44
Upside/Downside-6.21%
GradeOvervalued
TypeGrowth

Risk assessment

Beta2.78
Volatility57.55%
Sector RiskMedium
Reg. RiskHigh
Geo RiskLow
Currency RiskLow
Liquidity RiskLow

This analysis may contain inaccuracies and is provided for informational and research purposes only. It is not personal investment advice, a recommendation, or an instruction to buy, sell, or hold any asset.