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PSNL:NASDAQPersonalis, Inc. Analysis

Data as of 2026-08-23 - not real-time

$18.38

Latest Price

9/10Risk

Risk Level: High

Executive Summary

Personalis, Inc. trades at $18.38, with its short-term moving averages stacked above the longer-term ones — a bullish trend structure. Across the trailing 30 sessions it gained 30.6%. Relative strength is 77.3 — overbought — and the MACD signal is bullish. Watch $11.52 as support and $18.89 as the nearer resistance level.
The company is not currently profitable on a trailing basis, so earnings multiples offer no valuation support. Consensus targets land 24.5% below where the shares trade now. Revenue is growing at 30.0% on a -153.8% profit margin.
Risk comes out at 9 of a possible 10, a high reading. With 30-day volatility of 82.2%, a beta of 2.98 and a maximum drawdown of 55.2%, position sizing matters more than entry timing here. The wider market backdrop reads extreme greed at 94 on the fear-greed composite.
Timeframes disagree: the short-term read is hold while the long-term read is sell, conviction 4 out of 10.

Top Market Events

FREMONT, Calif. AP — FREMONT, Calif. AP — Personalis Inc. PSNL on Tuesday reported a loss of $31.7 million in its...Quick ReadModerna's Phase 3 mRNA cancer win sent TEM surging 24% and MRNA doubling over the past year, confirming...

Market Outlook

Short Term

< 1 year
Neutral
Model confidence: 1/10

Key Factors

  • Short-term moving averages stacked above long-term ones
  • RSI at 77.3 signals overbought conditions
  • Trading above the 200-day average of 9.43

Medium Term

1–3 years
Neutral
Model confidence: 1/10

Key Factors

  • Short-term moving averages stacked above long-term ones
  • RSI at 77.3 signals overbought conditions
  • Trading above the 200-day average of 9.43

Long Term

> 3 years
Cautious
Model confidence: 4/10

Key Factors

  • Negative profit margin of -153.8%
  • Analyst targets imply -24.5% versus the current price
  • Negative return on equity of -50.3%

Key Metrics & Analysis

Financial Health

Revenue Growth30.00%
Profit Margin-153.84%
P/E Ratio-19.5
ROE-50.32%
ROA-25.03%
Debt/Equity16.16
P/B Ratio8.3
Op. Cash Flow$-92298000
Free Cash Flow$-56028248
Industry P/E31.1

Technical Analysis

TrendBullish
RSI77.3
Support$11.52
Resistance$18.89
MA 20$13.90
MA 50$13.20
MA 200$9.43
MACDBullish
VolumeIncreasing
Fear & Greed Index94.41

Valuation

Target Price$13.88
Upside/Downside-24.51%
GradeOvervalued
TypeGrowth

Risk Assessment

Beta2.98
Volatility82.16%
Sector RiskMedium
Reg. RiskHigh
Geo RiskLow
Currency RiskLow
Liquidity RiskLow

This analysis may contain inaccuracies and is provided for informational and research purposes only. It is not personal investment advice, a recommendation, or an instruction to buy, sell, or hold any asset.