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PRME:NASDAQPrime Medicine, Inc. analysis

Data as of Oct 19, 2026 - not real-time

Latest price
$3.83
Risk: high
9/10High risk

Summary

Prime Medicine, Inc. trades at $3.83, with its short-term moving averages sitting below the longer-term ones — a bearish trend structure. Across the trailing 30 sessions it gained 3.4%. With RSI at 57.3 the momentum picture is neutral, alongside a bullish MACD signal. Recent trading has carved out support near $2.77 and resistance around $4.14.
The company is not currently profitable on a trailing basis, so earnings multiples offer no valuation support. Consensus targets land 86.0% above where the shares trade now. Revenue is growing at 3.5%.
Risk comes out at 9 of a possible 10, a high reading. With 30-day volatility of 112.0%, a beta of 2.28 and a maximum drawdown of 56.3%, position sizing matters more than entry timing here. The wider market backdrop reads extreme greed at 89 on the fear-greed composite.
The horizons diverge: hold near-term but sell on a long view, at 4/10 conviction over the longer horizon.

Top market events

  • -- Clearance highlights continued execution, modularity and momentum across Prime Medicine’s liver franchise,...
  • -- Clearance highlights continued execution, modularity and momentum across Prime Medicine's liver franchise, building...
  • Investing.com -- Prime Medicine Inc NASDAQ:PRME shares gained over 12% in after-hours trading Thursday following the...

Market outlook

Short term

< 1 year

Neutral

Model confidence3/103 out of 10

Key factors

  • Short-term moving averages stacked below long-term ones
  • Trading above the 200-day average of 3.48
  • MACD momentum is positive

Medium term

1–3 years

Neutral

Model confidence3/103 out of 10

Key factors

  • Short-term moving averages stacked below long-term ones
  • Trading above the 200-day average of 3.48
  • Analyst targets imply +86.0% versus the current price

Long term

> 3 years

Cautious

Model confidence4/104 out of 10

Key factors

  • Analyst targets imply +86.0% versus the current price
  • Negative return on equity of -373.3%
  • Negative free cash flow

Key metrics

Financial health

Revenue Growth3.50%
P/E Ratio-4.3
ROE-373.29%
ROA-46.52%
Debt/Equity282.54
P/B Ratio17.0
Op. Cash Flow$-156051008
Free Cash Flow$-75780000
Industry P/E31.4

Technical analysis

TrendBearish
RSI57.3
Support$2.77
Resistance$4.14
MA 20$3.34
MA 50$3.35
MA 200$3.48
MACDBullish
VolumeIncreasing
Fear & Greed Index88.82

Valuation

Target Price$7.11
Upside/Downside85.98%
GradeFair
TypeGrowth

Risk assessment

Beta2.28
Volatility111.97%
Sector RiskMedium
Reg. RiskHigh
Geo RiskLow
Currency RiskLow
Liquidity RiskMedium

This analysis may contain inaccuracies and is provided for informational and research purposes only. It is not personal investment advice, a recommendation, or an instruction to buy, sell, or hold any asset.