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PBYI:NASDAQPuma Biotechnology Inc Analysis

Data as of 2026-06-12 - not real-time

$7.23

Latest Price

7/10Risk

Risk Level: Medium

Executive Summary

Puma Biotechnology is trading at $7.23, just above its 20‑day SMA of $7.05 and comfortably above the 200‑day SMA of $6.07, indicating short‑term momentum while still respecting long‑term trend. The MACD histogram has turned positive and the signal line is bullish, with RSI at 54 suggesting the stock is neither overbought nor oversold. Support sits near $6.60 and resistance near $7.45, giving a modest upside window, while 30‑day volatility of over 33% signals a fairly swing‑prone price action. Fundamentally, the PE of 15 is well below the biotech industry average of 24.9 and the DCF fair value of $12.98 points to a substantial valuation gap, classifying the stock as undervalued. Recent earnings showed a narrower loss than expected and revenue of $44.8 M beat estimates, though year‑over‑year sales slipped 2.6%.
However, the company faces high sector and regulatory risk due to its reliance on product approvals and a pipeline still in trial phases, while its geographic exposure is limited to the United States and it carries no dividend obligations.

Market Outlook

Short Term

< 1 year
Positive
Model confidence: 6/10

Key Factors

  • Price above 20‑day SMA with bullish MACD
  • Valuation gap to DCF fair value
  • Stable volume and clear support level

Medium Term

1–3 years
Positive
Model confidence: 7/10

Key Factors

  • Revenue beat and narrowing loss in Q1
  • Pipeline potential for NERLYNX and alisertib
  • Undervalued PE relative to biotech peers

Long Term

> 3 years
Neutral
Model confidence: 6/10

Key Factors

  • High regulatory and sector risk
  • Dependence on future trial outcomes
  • No dividend, but solid cash position

Key Metrics & Analysis

Financial Health

Revenue Growth-2.60%
Profit Margin10.73%
P/E Ratio15.1
ROE21.62%
ROA9.48%
Debt/Equity12.42
P/B Ratio2.9
Op. Cash Flow$53.6M
Free Cash Flow$44.1M
Industry P/E24.9

Technical Analysis

TrendNeutral
RSI54.3
Support$6.60
Resistance$7.45
MA 20$7.05
MA 50$7.24
MA 200$6.07
MACDBullish
VolumeStable
Fear & Greed Index86.71

Valuation

Fair Value$12.98
Target Price$5.00
Upside/Downside-30.84%
GradeUndervalued
TypeBlend

Risk Assessment

Beta0.85
Volatility33.15%
Sector RiskHigh
Reg. RiskHigh
Geo RiskLow
Currency RiskLow
Liquidity RiskMedium

This analysis may contain inaccuracies and is provided for informational and research purposes only. It is not personal investment advice, a recommendation, or an instruction to buy, sell, or hold any asset.