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ORIC:NASDAQOric Pharmaceuticals, Inc. Analysis

Data as of 2026-04-22 - not real-time

$10.40

Latest Price

8/10Risk

Risk Level: High

Executive Summary

ORIC trades at $10.4, just below its 20‑day SMA of 10.44 and well under the 50‑day SMA of 11.35, indicating short‑term weakness. The RSI of 47.6 sits in neutral territory, while the MACD line sits above its signal (‑0.23 vs ‑0.35) producing a modest bullish histogram of 0.12. Price is perched near the computed support at $7.23 and has ample room to the resistance level of $13.04. Volatility is extreme at over 176 % (30‑day) and beta is around 1.0, suggesting the stock moves in line with the market but with amplified swings. The forward PE of ‑6.7 and a price‑to‑book of 2.66 contrast sharply with the industry average PE of 25.7, flagging a valuation disconnect. The Fear & Greed Index reads Extreme Greed (87.1), reflecting strong investor appetite despite the underlying risk profile.
ORIC is a clinical‑stage biotech with two Phase 1b candidates—enozertinib (ORIC‑114) and rinzimetostat (ORIC‑944)—and recent pre‑clinical data were presented at the 2026 AACR meeting. Strategic collaborations with Bayer and Johnson & Johnson add credibility and potential co‑development upside. The company carries no revenue, negative EBITDA of $‑141 M, and sizable cash of $281 M offset by a modest debt load, resulting in a negative ROE of ‑41 %. Analyst consensus rates the stock a Strong Buy with a median price target of $22, implying an upside of roughly 102 % from current levels. However, a 30‑day max drawdown of ‑48 % and a decreasing volume trend highlight liquidity concerns. Overall, the upside is driven by pipeline milestones, while the financial profile remains highly speculative.

Market Outlook

Short Term

< 1 year
Neutral
Model confidence: 6/10

Key Factors

  • bullish MACD histogram
  • price near support level
  • high volatility and decreasing volume

Medium Term

1–3 years
Positive
Model confidence: 7/10

Key Factors

  • pipeline progress on ORIC‑944 and ORIC‑114
  • strategic collaborations with Bayer and Johnson & Johnson
  • valuation upside to $22 median target

Long Term

> 3 years
Neutral
Model confidence: 5/10

Key Factors

  • potential for successful Phase 2/3 data
  • persistent cash burn and no revenue
  • high sector and regulatory risk

Key Metrics & Analysis

Financial Health

P/E Ratio-6.7
ROE-41.27%
ROA-26.17%
Debt/Equity1.94
P/B Ratio2.7
Op. Cash Flow$-110970000
Free Cash Flow$-69096496
Industry P/E25.7

Technical Analysis

TrendNeutral
RSI47.6
Support$7.23
Resistance$13.04
MA 20$10.44
MA 50$11.35
MA 200$11.04
MACDBullish
VolumeDecreasing
Fear & Greed Index87.13

Valuation

Target Price$21.00
Upside/Downside101.92%
GradeUndervalued
TypeBlend

Risk Assessment

Beta1.02
Volatility176.29%
Sector RiskHigh
Reg. RiskMedium
Geo RiskLow
Currency RiskLow
Liquidity RiskMedium

This analysis may contain inaccuracies and is provided for informational and research purposes only. It is not personal investment advice, a recommendation, or an instruction to buy, sell, or hold any asset.