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ONC:NASDAQBeOne Medicines Ltd. Analysis

Data as of 2026-06-18 - not real-time

$262.68

Latest Price

7/10Risk

Risk Level: Medium

Executive Summary

BeOne Medicines (ONC) trades at $262.68, well below its DCF‑derived fair value of $356.5, implying an upside of roughly 57% according to the model. The stock’s trailing P/E of 59.6 is markedly higher than the biotechnology industry average of 24.3, but the forward P/E of 27 and a projected EPS jump from $4.41 to $9.72 signal strong earnings acceleration. Revenue is expanding at a robust 35.5% YoY with an 88% gross margin and solid cash generation ($4.79 B cash vs $1.15 B debt, debt‑to‑equity 24%). Technical signals are mixed: the price sits below the 20‑, 50‑ and 200‑day SMAs, RSI is at 33 (oversold), and MACD remains bearish, yet volume is increasing and support at $254 provides a cushion above the current level. Recent material news includes a Phase 3 CLL/SLL dataset confirming long‑term benefit of BRUKINSA and new solid‑tumor data presented at ASCO, reinforcing pipeline momentum despite an insider sell on May 27. Overall, the combination of a deep cash position, accelerating earnings, and pipeline progress supports a bullish outlook, while valuation compression and sector volatility warrant caution.

Market Outlook

Short Term

< 1 year
Positive
Model confidence: 6/10

Key Factors

  • Oversold RSI near 33 suggests price floor
  • Increasing volume supports short‑term demand
  • Support level at $254 provides downside buffer

Medium Term

1–3 years
Positive
Model confidence: 8/10

Key Factors

  • Forward EPS growth and forward P/E of 27 indicate earnings upside
  • Phase 3 BRUKINSA data and ASCO solid‑tumor progress expand revenue runway
  • Strong cash position reduces financial distress risk

Long Term

> 3 years
Positive
Model confidence: 9/10

Key Factors

  • DCF fair value suggests ~57% upside over current price
  • Broad oncology pipeline across hematology and solid tumors offers diversification
  • Low beta (~0.78) and ample liquidity in a $27 B market cap mitigate market‑wide shocks

Key Metrics & Analysis

Financial Health

Revenue Growth35.50%
Profit Margin8.94%
P/E Ratio59.6
ROE12.42%
ROA5.96%
Debt/Equity24.14
P/B Ratio6.1
Op. Cash Flow$1.3B
Free Cash Flow$917.3M
Industry P/E24.3

Technical Analysis

TrendBearish
RSI33.2
Support$253.95
Resistance$312.01
MA 20$280.75
MA 50$296.37
MA 200$318.66
MACDBearish
VolumeIncreasing
Fear & Greed Index90.89

Valuation

Fair Value$356.49
Target Price$412.35
Upside/Downside56.98%
GradeUndervalued
TypeGrowth

Risk Assessment

Beta0.78
Volatility33.87%
Sector RiskHigh
Reg. RiskHigh
Geo RiskMedium
Currency RiskMedium
Liquidity RiskLow

This analysis may contain inaccuracies and is provided for informational and research purposes only. It is not personal investment advice, a recommendation, or an instruction to buy, sell, or hold any asset.