ONC:NASDAQBeOne Medicines Ltd. Analysis
Data as of 2026-06-18 - not real-time
$262.68
Latest Price
7/10Risk
Risk Level: Medium
Executive Summary
BeOne Medicines (ONC) trades at $262.68, well below its DCF‑derived fair value of $356.5, implying an upside of roughly 57% according to the model. The stock’s trailing P/E of 59.6 is markedly higher than the biotechnology industry average of 24.3, but the forward P/E of 27 and a projected EPS jump from $4.41 to $9.72 signal strong earnings acceleration. Revenue is expanding at a robust 35.5% YoY with an 88% gross margin and solid cash generation ($4.79 B cash vs $1.15 B debt, debt‑to‑equity 24%). Technical signals are mixed: the price sits below the 20‑, 50‑ and 200‑day SMAs, RSI is at 33 (oversold), and MACD remains bearish, yet volume is increasing and support at $254 provides a cushion above the current level. Recent material news includes a Phase 3 CLL/SLL dataset confirming long‑term benefit of BRUKINSA and new solid‑tumor data presented at ASCO, reinforcing pipeline momentum despite an insider sell on May 27. Overall, the combination of a deep cash position, accelerating earnings, and pipeline progress supports a bullish outlook, while valuation compression and sector volatility warrant caution.
Market Outlook
Short Term
< 1 yearPositive
Model confidence: 6/10
Key Factors
- Oversold RSI near 33 suggests price floor
- Increasing volume supports short‑term demand
- Support level at $254 provides downside buffer
Medium Term
1–3 yearsPositive
Model confidence: 8/10
Key Factors
- Forward EPS growth and forward P/E of 27 indicate earnings upside
- Phase 3 BRUKINSA data and ASCO solid‑tumor progress expand revenue runway
- Strong cash position reduces financial distress risk
Long Term
> 3 yearsPositive
Model confidence: 9/10
Key Factors
- DCF fair value suggests ~57% upside over current price
- Broad oncology pipeline across hematology and solid tumors offers diversification
- Low beta (~0.78) and ample liquidity in a $27 B market cap mitigate market‑wide shocks
Key Metrics & Analysis
Financial Health
Revenue Growth35.50%
Profit Margin8.94%
P/E Ratio59.6
ROE12.42%
ROA5.96%
Debt/Equity24.14
P/B Ratio6.1
Op. Cash Flow$1.3B
Free Cash Flow$917.3M
Industry P/E24.3
Technical Analysis
TrendBearish
RSI33.2
Support$253.95
Resistance$312.01
MA 20$280.75
MA 50$296.37
MA 200$318.66
MACDBearish
VolumeIncreasing
Fear & Greed Index90.89
Valuation
Fair Value$356.49
Target Price$412.35
Upside/Downside56.98%
GradeUndervalued
TypeGrowth
Risk Assessment
Beta0.78
Volatility33.87%
Sector RiskHigh
Reg. RiskHigh
Geo RiskMedium
Currency RiskMedium
Liquidity RiskLow
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This analysis may contain inaccuracies and is provided for informational and research purposes only. It is not personal investment advice, a recommendation, or an instruction to buy, sell, or hold any asset.