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ONC:NASDAQBeOne Medicines Ltd. Analysis

Data as of 2026-04-22 - not real-time

$311.04

Latest Price

6/10Risk

Risk Level: Medium

Executive Summary

Technical outlook: The 20‑day SMA sits below the 50‑day SMA and both are under the 200‑day SMA, reinforcing a bearish alignment despite a bullish MACD histogram. The RSI hovers near the midpoint, suggesting no immediate overbought or oversold condition, while the 30‑day volatility remains elevated, implying sizable price swings. Fundamental backdrop: Revenue is expanding at a robust pace with an exceptionally high gross margin, and the company boasts a strong cash pile and modest debt, delivering a low‑leverage profile. However, the trailing P/E is dramatically above the industry average, and the current market price exceeds the DCF‑derived fair value, flagging a significant valuation premium. Recent material news includes an FDA orphan‑drug designation for a liver‑cancer candidate and fresh analyst coverage, which have sparked short‑term price enthusiasm, yet a downgrade from Jefferies tempers optimism. Overall, the stock sits at the intersection of strong growth engines and pronounced valuation and technical headwinds.

Market Outlook

Short Term

< 1 year
Neutral
Model confidence: 6/10

Key Factors

  • Recent FDA orphan‑drug designation creating near‑term catalyst
  • Bullish MACD against a broader bearish trend
  • Elevated volatility and overvalued pricing

Medium Term

1–3 years
Positive
Model confidence: 7/10

Key Factors

  • Sustained revenue growth and high gross margins
  • Robust cash position with low leverage
  • Pipeline diversification across multiple oncology modalities

Long Term

> 3 years
Positive
Model confidence: 8/10

Key Factors

  • Long‑term demand for innovative cancer therapies
  • Strategic partnerships with major pharma players
  • Potential upside from upcoming clinical readouts and market expansions

Key Metrics & Analysis

Financial Health

Revenue Growth32.80%
Profit Margin5.37%
P/E Ratio125.9
ROE7.46%
ROA3.96%
Debt/Equity25.06
P/B Ratio7.9
Op. Cash Flow$1.1B
Free Cash Flow$727.1M
Industry P/E25.8

Technical Analysis

TrendBearish
RSI52.2
Support$272.02
Resistance$328.39
MA 20$305.34
MA 50$312.28
MA 200$319.17
MACDBullish
VolumeStable
Fear & Greed Index86.71

Valuation

Fair Value$266.48
Target Price$408.20
Upside/Downside31.24%
GradeOvervalued
TypeGrowth

Risk Assessment

Beta0.65
Volatility33.85%
Sector RiskHigh
Reg. RiskHigh
Geo RiskMedium
Currency RiskLow
Liquidity RiskMedium

This analysis may contain inaccuracies and is provided for informational and research purposes only. It is not personal investment advice, a recommendation, or an instruction to buy, sell, or hold any asset.