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MREO:NASDAQMereo BioPharma Group plc analysis

Data as of Sep 1, 2026 - not real-time

Latest price
$0.27
Risk: high
9/10High risk

Summary

At $0.2668, Mereo BioPharma Group plc shows a bearish moving-average alignment, with shorter averages beneath longer ones. The last 30 days have lost 12.5%. Relative strength is 39.6 — approaching oversold — and the MACD signal is bearish. Recent trading has carved out support near $0.2520 and resistance around $0.3700.
The company is not currently profitable on a trailing basis, so earnings multiples offer no valuation support. Consensus targets land 650.1% above where the shares trade now.
The composite risk read is 9/10, putting it in high territory. With 30-day volatility of 72.7%, a beta of 1.50 and a maximum drawdown of 89.7%, position sizing matters more than entry timing here. The wider market backdrop reads extreme greed at 95 on the fear-greed composite.
This one splits by horizon — sell in the near term, hold further out, at 1/10 long-term conviction.

Top market events

  • Entered into option and license agreement with Sentynl Therapeutics for alvelestat, Mereo’s investigational oral...
  • Entered into option and license agreement with Sentynl Therapeutics for alvelestat, Mereo's investigational oral...
  • Sentynl Therapeutics, Inc. "Sentynl" , a U.S.-based biopharmaceutical company and wholly-owned subsidiary of Zydus...

Market outlook

Short term

< 1 year

Cautious

Model confidence4/104 out of 10

Key factors

  • Short-term moving averages stacked below long-term ones
  • Trading below the 200-day average of 0.60
  • MACD momentum is negative

Medium term

1–3 years

Neutral

Model confidence2/102 out of 10

Key factors

  • Short-term moving averages stacked below long-term ones
  • Trading below the 200-day average of 0.60
  • Analyst targets imply +650.1% versus the current price

Long term

> 3 years

Neutral

Model confidence1/101 out of 10

Key factors

  • Analyst targets imply +650.1% versus the current price
  • Negative return on equity of -67.8%
  • Negative free cash flow

Key metrics

Financial health

P/E Ratio-11.4
ROE-67.85%
ROA-42.46%
Debt/Equity3.60
P/B Ratio1.5
Op. Cash Flow$-25346000
Free Cash Flow$-13656500
Industry P/E30.4

Technical analysis

TrendBearish
RSI39.6
Support$0.25
Resistance$0.37
MA 20$0.29
MA 50$0.31
MA 200$0.60
MACDBearish
VolumeDecreasing
Fear & Greed Index94.79

Valuation

Target Price$2.00
Upside/Downside650.10%
GradeFair
TypeBlend

Risk assessment

Beta1.50
Volatility72.66%
Sector RiskMedium
Reg. RiskHigh
Geo RiskLow
Currency RiskLow
Liquidity RiskMedium

This analysis may contain inaccuracies and is provided for informational and research purposes only. It is not personal investment advice, a recommendation, or an instruction to buy, sell, or hold any asset.