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LYEL:NASDAQLyell Immunopharma, Inc. analysis

Data as of Sep 5, 2026 - not real-time

Latest price
$14.37
Risk: high
9/10High risk

Summary

Lyell Immunopharma, Inc. is priced at $14.37, and its moving averages give no clean directional read — the structure is neutral. Over a rolling month the price has gained 13.8%. With RSI at 49.3 the momentum picture is neutral, alongside a bearish MACD signal. Recent trading has carved out support near $13.39 and resistance around $17.15.
The company is not currently profitable on a trailing basis, so earnings multiples offer no valuation support. Sell-side targets cluster 163.6% above the current quote. Revenue is contracting at 50.0%.
Risk comes out at 9 of a possible 10, a high reading. With 30-day volatility of 69.4%, a beta of 1.72 and a maximum drawdown of 69.9%, position sizing matters more than entry timing here. The wider market backdrop reads extreme greed at 95 on the fear-greed composite.
Short, medium and long-term reads agree on hold, with conviction of 1/10.

Top market events

  • PiNACLE pivotal clinical trial evaluating ronde-cel in 3L+ patients with LBCL on track to report additional data in...
  • SOUTH SAN FRANCISCO, Calif. AP — SOUTH SAN FRANCISCO, Calif. AP — Lyell Immunopharma Inc. LYEL on Thursday reported...
  • The latest company information, including net asset values, performance, holding & sectors weighting, changes in voting...

Market outlook

Short term

< 1 year

Neutral

Model confidence2/102 out of 10

Key factors

  • Trading below the 200-day average of 20.30
  • MACD momentum is negative
  • 30-day price change of +13.8%

Medium term

1–3 years

Neutral

Model confidence2/102 out of 10

Key factors

  • Trading below the 200-day average of 20.30
  • Analyst targets imply +163.6% versus the current price
  • 30-day volatility of 69.4%

Long term

> 3 years

Neutral

Model confidence1/101 out of 10

Key factors

  • Analyst targets imply +163.6% versus the current price
  • Negative return on equity of -93.3%
  • Revenue contracting at -50.0%

Key metrics

Financial health

Revenue Growth-50.00%
P/E Ratio-2.3
ROE-93.28%
ROA-34.18%
Debt/Equity19.93
P/B Ratio1.4
Op. Cash Flow$-133260000
Free Cash Flow$-72809128
Industry P/E30.6

Technical analysis

TrendNeutral
RSI49.3
Support$13.39
Resistance$17.15
MA 20$14.69
MA 50$14.05
MA 200$20.30
MACDBearish
VolumeDecreasing
Fear & Greed Index95.48

Valuation

Target Price$37.88
Upside/Downside163.57%
GradeFair
TypeBlend

Risk assessment

Beta1.72
Volatility69.45%
Sector RiskMedium
Reg. RiskHigh
Geo RiskLow
Currency RiskLow
Liquidity RiskMedium

This analysis may contain inaccuracies and is provided for informational and research purposes only. It is not personal investment advice, a recommendation, or an instruction to buy, sell, or hold any asset.