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KRYS:NASDAQKrystal Biotech, Inc. Analysis

Data as of 2026-06-13 - not real-time

$317.97

Latest Price

6/10Risk

Risk Level: Medium

Executive Summary

Krystal Biotech’s price is trading well above its 20‑day SMA (304.55) and comfortably between the 50‑day (288.29) and 200‑day (240.48) averages, indicating strong upward momentum. Technical indicators such as a bullish MACD histogram (+0.56) and a RSI of 61.6 reinforce a near‑term buying bias. The stock sits on a solid support base of 285.07 and faces resistance near 331.49, while volume trends are increasing, suggesting liquidity is improving. Fundamental metrics reveal a revenue growth rate of 31.9% with gross margins near 94% and operating margins above 46%, underscoring a high‑margin, fast‑growing business model. However, the trailing P/E of 42.6 versus an industry average of 24.8 points to a potentially overvalued valuation, tempered by a robust cash position (~$824 M) and minimal debt (~$9 M). Recent regulatory news – the UK approval of VYJUVEK for DEB – adds a concrete catalyst that could mitigate valuation concerns in the medium term. Overall, the stock exhibits bullish technicals and strong fundamentals but carries valuation and sector‑specific risk that must be managed.

Market Outlook

Short Term

< 1 year
Positive
Model confidence: 7/10

Key Factors

  • bullish MACD histogram and RSI indicating upward price pressure
  • price above 20‑day SMA and strong support at 285.07
  • increasing volume trend enhancing short‑term liquidity

Medium Term

1–3 years
Neutral
Model confidence: 6/10

Key Factors

  • recent UK regulatory approval of VYJUVEK providing a tangible catalyst
  • high revenue growth and margin profile supporting sustainable earnings
  • large cash reserve and low debt reducing financial distress risk

Long Term

> 3 years
Neutral
Model confidence: 7/10

Key Factors

  • pipeline depth across multiple genetic therapies offering future upside
  • strong balance sheet with $823 M cash and minimal leverage
  • valuation compression risk due to P/E far above industry average

Key Metrics & Analysis

Financial Health

Revenue Growth31.90%
Profit Margin53.92%
P/E Ratio42.6
ROE19.90%
ROA9.04%
Debt/Equity0.71
P/B Ratio7.3
Op. Cash Flow$250.3M
Free Cash Flow$137.5M
Industry P/E24.8

Technical Analysis

TrendBullish
RSI61.6
Support$285.07
Resistance$331.49
MA 20$304.55
MA 50$288.29
MA 200$240.48
MACDBullish
VolumeIncreasing
Fear & Greed Index89.86

Valuation

Fair Value$196.62
Target Price$322.78
Upside/Downside1.51%
GradeOvervalued
TypeGrowth

Risk Assessment

Beta0.90
Volatility38.92%
Sector RiskHigh
Reg. RiskMedium
Geo RiskLow
Currency RiskLow
Liquidity RiskMedium

This analysis may contain inaccuracies and is provided for informational and research purposes only. It is not personal investment advice, a recommendation, or an instruction to buy, sell, or hold any asset.