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AZN:LSEAstraZeneca PLC Analysis

Data as of 2026-05-18 - not real-time

£13,710.00

Latest Price

4/10Risk

Risk Level: Medium

Executive Summary

AstraZeneca is delivering solid top‑line growth with double‑digit expansion in oncology and rare disease, while maintaining strong operating margins and robust free cash flow that comfortably cover its dividend. The company’s low beta and increasing volume suggest a defensive profile with growing investor interest, and the current dividend yield of around 1.7% appears sustainable given a payout ratio below 50% and ample cash generation.
Technically, the stock trades just above its 20‑day simple moving average, the RSI sits in the mid‑40s indicating no extreme overbought or oversold pressure, and the MACD histogram has turned positive, signaling a modest bullish bias despite a neutral overall trend. However, the discounted cash‑flow model places fair value well below the market price, implying limited upside in the near term unless the pipeline—particularly the emerging RNA‑targeted small‑molecule platform—accelerates revenue growth.

Market Outlook

Short Term

< 1 year
Neutral
Model confidence: 7/10

Key Factors

  • Positive MACD histogram indicating short‑term momentum
  • Market price above DCF fair value limiting immediate upside
  • Stable dividend and low beta supporting defensive positioning

Medium Term

1–3 years
Positive
Model confidence: 8/10

Key Factors

  • Sustained revenue growth driven by oncology and rare‑disease franchises
  • Forward P/E compression suggesting cheaper valuation ahead
  • Strategic RNA‑targeted therapeutics pipeline expanding growth avenues

Long Term

> 3 years
Positive
Model confidence: 8/10

Key Factors

  • Strong cash conversion and dividend sustainability
  • Long‑term partnerships enhancing R&D productivity
  • Global diversification mitigating geographic concentration risk

Key Metrics & Analysis

Financial Health

Revenue Growth12.50%
Profit Margin17.19%
P/E Ratio27.9
ROE23.48%
ROA8.47%
Debt/Equity71.81
P/B Ratio6.1
Op. Cash Flow£14.2B
Free Cash Flow£6.5B
Industry P/E26.9

Technical Analysis

TrendNeutral
RSI43.7
Support£12,356.00
Resistance£15,108.00
MA 20£13,859.19
MA 50£14,291.36
MA 200£13,378.60
MACDBullish
VolumeIncreasing
Fear & Greed Index89.61

Valuation

Fair Value£7,531.79
Target Price£16,498.26
Upside/Downside20.34%
GradeOvervalued
TypeBlend
Dividend Yield1.73%

Risk Assessment

Beta0.19
Volatility24.60%
Sector RiskMedium
Reg. RiskMedium
Geo RiskMedium
Currency RiskLow
Liquidity RiskLow

This analysis may contain inaccuracies and is provided for informational and research purposes only. It is not personal investment advice, a recommendation, or an instruction to buy, sell, or hold any asset.